Palazzo Tiglio lies in the small hamlet of San Pancrazio, perched on a hilltop overlooking the magnificent Valdambra. This small village once belonged to the important Ubertini family of Arezzo before coming under the protection of the Marchesato di Bucine and the Grand Duchy of Florence.
The current Palazzo Tiglio was built in the 17th century on medieval foundations. When restoring the ancient cellars both a medieval water well and ancient grain storages cut in to the rock, thought to be from roman times, were found.
During history the palazzo has belonged to many different families, both of noble origins and local dignitaries. In the entrance staircase the coat of arms of the previous owners, the Scodellini family has been painted.